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Medchemexpress/腺苷蛋氨酸（同义词：S-腺苷-L-蛋氨酸；S-腺苷甲硫氨酸；相同；AdoMet）/HY-B0617/500mg
| Description |
Ademetionine(S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. Target: Others S-adenosyl-l-methionine (SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior with that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side-effects, it is a potentially important treatment for depression [1]. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee [2]. |
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| Clinical Trial |
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| References |
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| Preparing Stock Solutions |
Please refer to the solubility information to select the appropriate solvent.
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| References |
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| Molecular Weight |
398.44 |
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| Formula |
C₁₅H₂₂N₆O₅S |
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| CAS No. |
29908-03-0 |
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| Storage |
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| Shipping | Room temperature in continental US; may vary elsewhere |
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| Solvent & Solubility |
H2O: ≥ 43 mg/mL; DMSO: ≥100 mg/mL (Need ultrasonic)
* "<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation=""> |
Purity: >98.0%
COA (94 KB) HNMR (189 KB) MS (207 KB)
Handling Instructions (1252 KB)-
[1]. Bressa, G.M., S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl, 1994. 154: p. 7-14.
[2]. Najm, W.I., et al., S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord, 2004. 5: p. 6.
