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当前位置： 首页 > 产品中心 > Small_molecule > Medchemexpress/腺苷蛋氨酸（同义词：S-腺苷-L-蛋氨酸；S-腺苷甲硫氨酸；相同；AdoMet）/HY-B0617/100mg
商品详细Medchemexpress/腺苷蛋氨酸（同义词：S-腺苷-L-蛋氨酸；S-腺苷甲硫氨酸；相同；AdoMet）/HY-B0617/100mg
Medchemexpress/腺苷蛋氨酸（同义词：S-腺苷-L-蛋氨酸；S-腺苷甲硫氨酸；相同；AdoMet）/HY-B0617/100mg
Medchemexpress/腺苷蛋氨酸（同义词：S-腺苷-L-蛋氨酸；S-腺苷甲硫氨酸；相同；AdoMet）/HY-B0617/100mg
商品编号： HY-B0617-50mg
品牌： MedChemExp
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产地： 美国(厂家直采)
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产品分类： 小分子
公司分类： Small_molecule
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商品介绍
Ademetionine(S-adenosyl-l-methionine;SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.
Description

Ademetionine(S-adenosyl-l-methionine;SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.Target:OthersS-adenosyl-l-methionine(SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.TheefficacyofSAMeintreatingdepressivesyndromesanddisordersissuperiorwiththatofplaceboandcomparabletothatofstandardtricyclicantidepressants.SinceSAMeisanaturallyoccurringcompoundwithrelativelyfewside-effects,itisapotentiallyimportanttreatmentfordepression[1].S-adenosylmethionine(SAMe)isadietarysupplementusedinthemanagementofosteoarthritis(OA)symptoms.StudiesevaluatingSAMeinthemanagementofOAhavebeenlimitedtoNonSteroidalAnti-inflammatoryDrugs(NSAIDs)forcomparison.ThepresentstudycomparestheeffectivenessofSAMetoacyclooxygenase-2(COX-2)inhibitor(celecoxib)forpaincontrol,functionalimprovementandtodecreasesideeffectsinpeoplewithosteoarthritisoftheknee[2].

ClinicalTrial
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References

  • [1].Bressa,G.M.,S-adenosyl-l-methionine(SAMe)asantidepressant:meta-analysisofclinicalstudies.ActaNeurolScandSuppl,1994.154:p.7-14.

    [2].Najm,W.I.,etal.,S-adenosylmethionine(SAMe)versuscelecoxibforthetreatmentofosteoarthritissymptoms:adouble-blindcross-overtrial.[ISRCTN36233495].BMCMusculoskeletDisord,2004.5:p.6.

PreparingStockSolutions
ConcentrationVolumeMass1mg5mg10mg
1mM2.5098mL12.5489mL25.0979mL
5mM0.5020mL2.5098mL5.0196mL
10mM0.2510mL1.2549mL2.5098mL
Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent.
References

  • [1].Bressa,G.M.,S-adenosyl-l-methionine(SAMe)asantidepressant:meta-analysisofclinicalstudies.ActaNeurolScandSuppl,1994.154:p.7-14.

    [2].Najm,W.I.,etal.,S-adenosylmethionine(SAMe)versuscelecoxibforthetreatmentofosteoarthritissymptoms:adouble-blindcross-overtrial.[ISRCTN36233495].BMCMusculoskeletDisord,2004.5:p.6.

MolecularWeight

398.44

Formula

C₁₅H₂₂N₆O₅S

CASNo.

29908-03-0

Storage
Powder-20°C3years
 4°C2years
Insolvent-80°C6months
 -20°C1month
Shipping

RoomtemperatureincontinentalUS;mayvaryelsewhere

Solvent&Solubility

H2O:≥43mg/mL;DMSO:≥100mg/mL(Needultrasonic)

*"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">

Purity:>98.0%